Correlative 3D cryo X-ray imaging reveals intracellular location and effect of designed antifibrotic protein–nanomaterial hybrids

Author: J. Groen, A. Palanca,A. Aires, J. J. Conesa, D. Maestro, S. Rehbein, M. Harkiolaki, A. V. Villar,A. L. Cortajarena, and  E. Pereiro.​

Abstract:
Revealing the intracellular location of novel therapeutic agents is paramount for the understanding of their effect at the cell ultrastructure level. Here, we apply a novel correlative cryo 3D imaging approach to determine the intracellular fate of a designed​…